Single nucleotide polymorphisms (SNPs) are often close enough together to permit simultaneous identification with a single DUPLEXER™ reagent. This is common in genes with multiple genetic
defects which contribute to inherited diseases (e.g. Canavan Disease or von Willebrands disease). The below gel demonstrates detection of mutiple SNP's within Canavan's E285A / A305E.
Canavan E285A/A305E Gel showing induced heteroduplexes
